LOCUS       HUMMYCC     10996 bp    DNA             PRI       25-JUL-1994
DEFINITION  Human (Lawn) c-myc proto-oncogene, complete coding sequence and
            flanks.
ACCESSION   J00120 K01908 M23541 V00501 X00364
VERSION     J00120.1  GI:515632
KEYWORDS    Alu repeat; c-myc proto-oncogene; myc oncogene; proto-oncogene;
            repeat region; transforming gene.
SOURCE      Human DNA (genomic library of Lawn et al.), clones lambda-M1 [1],
            and pUC9-myc [2].
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 3507 to 7559)
  AUTHORS   Colby,W.W., Chen,E.Y., Smith,D.H. and Levinson,A.D.
  TITLE     Identification and nucleotide sequence of a human locus homologous
            to the v-myc oncogene of avian myelocytomatosis virus MC29
  JOURNAL   Nature 301 (5902), 722-725 (1983)
  MEDLINE   83141777
REFERENCE   2  (bases 1 to 8082)
  AUTHORS   Gazin,C., Dupont de Dinechin,S., Hampe,A., Masson,J.M., Martin,P.,
            Stehelin,D. and Galibert,F.
  TITLE     Nucleotide sequence of the human c-myc locus: provocative open
            reading frame within the first exon
  JOURNAL   EMBO J. 3 (2), 383-387 (1984)
  MEDLINE   84182501
REFERENCE   3  (bases 8083 to 10996)
  AUTHORS   Guilhot,S., Petridou,B., Syed-Hussain,S. and Galibert,F.
  TITLE     Nucleotide sequence 3' to the human c-myc oncogene; Presence of a
            long inverted repeat
  JOURNAL   Gene 72, 105-108 (1988)
  MEDLINE   89211899
COMMENT     On Jul 25, 1994 this sequence version replaced gi:188923.
            The myc gene is the cellular homologue of the transforming gene
            carried by the avian myelocytomatosis virus MC29. Unlike the ras
            proto-oncogenes which obtain transforming potential through
            mutations within their coding exons (namely mutations within codon
            12), the myc gene identified as the cause of Burkitt lymphomas
            acquires its transforming potential through defects of either
            transcriptional or translational control. Thus it is not an altered
            gene product that induces tumors, but a normal product that is
            present either in the wrong quantity or at the wrong time in the
            life cycle of the cell.  
               
            [2] notes an open reading frame upstream of the c-myc coding exons
            with an 'atg' start codon at bases 2304-2306 and a 'tag' stop codon
            at bases 2868-2870. However other researchers have used c-myc and
            v-myc DNA sequences to probe for mRNA's with homology to c-myc in
            various human cell lines and none of them have noted any mRNA's
            beginning upstream of bp 2328 (see other human c-myc entries).  
               
            The t(8;14) translocation site in the Burkitt lymphoma cell line
            BL22 occurs between bp 1316 and 1317 of this sequence.  
               
            See other human c-myc entries.
FEATURES             Location/Qualifiers
     source          1..10996
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /map="8q24"
     CDS             2304..2870
                     /note="ORF1"
                     /codon_start=1
                     /protein_id="AAA20041.1"
                     /db_xref="GI:515633"
                     /translation="MRGSGRLRTPELCCSRPPPPGPGRPWLPSCLEKGRASQRLGGKK
                     NGGRDRAEYKSRFSGLYLTRCSNSSERQRERAGGRLGWKSRASRAALRASWEGRSGAN
                     RGLRLWPSPPADPPASGPQPLPHPRNFAHSSGRALCTGTYNTRARTRLSRRGEAILPI
                     WGHFPAAARTRFSERLSLQLLRRWIFFG"
     gene            2327..7657
                     /gene="MYC"
     exon            2327..2881
                     /gene="MYC"
                     /note="alternative exon"
                     /number=1
     mRNA            join(2327..2881,4506..5277,6654..>7216)
                     /gene="MYC"
     exon            2502..2881
                     /gene="MYC"
                     /note="alternative exon"
                     /number=1
     mRNA            join(2502..2881,4506..5277,6654..>7216)
                     /gene="MYC"
     intron          2882..4505
                     /gene="MYC"
                     /number=1
     exon            4506..5277
                     /gene="MYC"
                     /number=2
     CDS             join(4521..5277,6654..7216)
                     /gene="MYC"
                     /codon_start=1
                     /product="c-myc protein"
                     /protein_id="AAA20042.1"
                     /db_xref="GI:386965"
                     /translation="MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPA
                     PSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMV
                     TELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSG
                     SPNPARGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSP
                     SSDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKR
                     SESGSPSAGGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLR
                     QISNNRKCTSPRSSDTEENVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPK
                     VVILKKATAYILSVQAEEQKLISEEDLLRKRREQLKHKLEQLRNSCA"
     intron          5278..6653
                     /gene="MYC"
                     /number=2
     repeat_region   6299..6466
                     /note="Alu-like repeat"
                     /rpt_family="Alu"
     exon            6654..7216
                     /gene="MYC"
                     /number=3
     polyA_signal    7511..7516
                     /gene="MYC"
     polyA_signal    7652..7657
                     /gene="MYC"
BASE COUNT     2747 a   2723 c   2733 g   2793 t
ORIGIN      198 bp upstream of Sau96A site, on chromosome 8 (q24).
        1 agcttgtttg gccgttttag ggtttgttgg aatttttttt tcgtctatgt acttgtgaat
       61 tatttcacgt ttgccattac cggttctcca tagggtgatg ttcattagca gtggtgatag
      121 gttaattttc accatctctt atgcggttga atagtcacct ctgaaccact ttttcctcca
      181 gtaactcctc tttcttcgga ccttctgcag ccaacctgaa agaataacaa ggaggtggct
      241 ggaaacttgt tttaaggaac cgcctgtcct tcccccgctg gaaaccttgc acctcggacg
      301 ctcctgctcc tgcccccacc tgacccccgc cctcgttgac atccaggcgc gatgatctct
      361 gctgccagta gagggcacac ttactttact ttcgcaaacc tgaacgcggg tgctgcccag
      421 agagggggcg gagggaaaga cgctttgcag caaaatccag catagcgatt ggttgctccc
      481 cgcgtttgcg gcaaaggcct ggaggcagga gtaatttgca atccttaaag ctgaattgtg
      541 cagtgcatcg gatttggaag ctactatatt cacttaacac ttgaacgctg agctgcaaac
      601 tcaacgggta ataacccatc ttgaacagcg tacatgctat acacacaccc ctttcccccg
      661 aattgttttc tcttttggag gtggtggagg gagagaaaag tttacttaaa atgcctttgg
      721 gtgagggacc aaggatgaga agaatgtttt ttgtttttca tgccgtggaa taacacaaaa
      781 taaaaaatcc cgagggaata tacattatat attaaatata gatcatttca gggagcaaac
      841 aaatcatgtg tggggctggg caactagctg agtcgaagcg taaataaaat gtgaatacac
      901 gtttgcgggt tacatacagt gcactttcac tagtattcag aaaaaattgt gagtcagtga
      961 actaggaaat taatgcctgg aaggcagcca aattttaatt agctcaagac tccccccccc
     1021 ccccaaaaaa aggcacggaa gtaatactcc tctcctcttc tttgatcaga atcgatgcat
     1081 tttttgtgca tgaccgcatt tccaataata aaaggggaaa gaggacctgg aaaggaatta
     1141 aacgtccggt ttgtccgggg aggaaagagt taacggtttt tttcacaagg gtctctgctg
     1201 actcccccgg ctcggtccac aagctctcca cttgcccctt ttaggaagtc cggtcccgcg
     1261 gttcgggtac cccctgcccc tcccatattc tcccgtctag cacctttgat ttctcccaaa
     1321 cccggcagcc cgagactgtt gcaaaccggc gccacagggc gcaaagggga tttgtctctt
     1381 ctgaaacctg gctgagaaat tgggaactcc gtgtgggagg cgtgggggtg ggacggtggg
     1441 gtacagactg gcagagagca ggcaacctcc ctctcgccct agcccagctc tggaacaggc
     1501 agacacatct cagggctaaa cagacgcctc ccgcacgggg ccccacggaa gcctgagcag
     1561 gcggggcagg aggggcggta tctgctgctt tggcagcaaa ttgggggact cagtctgggt
     1621 ggaaggtatc caatccagat agctgtgcat acataatgca taatacatga ctccccccaa
     1681 caaatgcaat gggagtttat tcataacgcg ctctccaagt atacgtggca atgcgttgct
     1741 gggttatttt aatcattcta ggcatcgttt tcctccttat gcctctatca ttcctcccta
     1801 tctacactaa catcccacgc tctgaacgcg cgcccattaa tacccttctt tcctccactc
     1861 tccctgggac tcttgatcaa agcgcggccc tttccccagc cttagcgagg cgccctgcag
     1921 cctggtacgc gcgtggcgtg gcggtgggcg cgcagtgcgt tctctgtgtg gagggcagct
     1981 gttccgcctg cgatgattta tactcacagg acaaggatgc ggtttgtcaa acagtactgc
     2041 tacggaggag cagcagagaa agggagaggg tttgagaggg agcaaaagaa aatggtaggc
     2101 gcgcgtagtt aattcatgcg gctctcttac tctgtttaca tcctagagct agagtgctcg
     2161 gctgcccggc tgagtctcct ccccaccttc cccaccctcc ccaccctccc cataagcgcc
     2221 cctcccgggt tcccaaagca gagggcgtgg gggaaaagaa aaaagatcct ctctcgctaa
     2281 tctccgccca ccggcccttt ataatgcgag ggtctggacg gctgaggacc cccgagctgt
     2341 gctgctcgcg gccgccaccg ccgggccccg gccgtccctg gctcccctcc tgcctcgaga
     2401 agggcagggc ttctcagagg cttggcggga aaaagaacgg agggagggat cgcgctgagt
     2461 ataaaagccg gttttcgggg ctttatctaa ctcgctgtag taattccagc gagaggcaga
     2521 gggagcgagc gggcggccgg ctagggtgga agagccgggc gagcagagct gcgctgcggg
     2581 cgtcctggga agggagatcc ggagcgaata gggggcttcg cctctggccc agccctcccg
     2641 ctgatccccc agccagcggt ccgcaaccct tgccgcatcc acgaaacttt gcccatagca
     2701 gcgggcgggc actttgcact ggaacttaca acacccgagc aaggacgcga ctctcccgac
     2761 gcggggaggc tattctgccc atttggggac acttccccgc cgctgccagg acccgcttct
     2821 ctgaaaggct ctccttgcag ctgcttagac gctggatttt tttcgggtag tggaaaacca
     2881 ggtaagcacc gaagtccact tgccttttaa tttatttttt tatcacttta atgctgagat
     2941 gagtcgaatg cctaaatagg gtgtcttttc tcccattcct gcgctattga cacttttctc
     3001 agagtagtta tggtaactgg ggctggggtg gggggtaatc cagaactgga tcggggtaaa
     3061 gtgacttgtc aagatgggag aggagaaggc agagggaaaa cgggaatggt ttttaagact
     3121 accctttcga gatttctgcc ttatgaatat attcacgctg actcccggcc ggtcggacat
     3181 tcctgcttta ttgtgttaat tgctctctgg gttttggggg gctgggggtt gctttgcggt
     3241 gggcagaaag ccccttgcat cctgagctcc ttggagtagg gaccgcatat cgcctgtgtg
     3301 agccagatcg ctccgcagcc gctgacttgt ccccgtctcc gggagggcat ttaaatttcg
     3361 gctcaccgca tttctgacag ccggagacgg acactgcggc gcgtcccgcc cgcctgtccc
     3421 cgcggcgatt ccaacccgcc ctgatccttt taagaagttg gcatttggct ttttaaaaag
     3481 caataataca atttaaaacc tgggtctcta gaggtgttag gacgtggtgt tgggtaggcg
     3541 caggcagggg aaaagggagg cgaggatgtg tccgattctc ctggaatcgt tgacttggaa
     3601 aaaccagggc gaatctccgc acccagccct gactcccctg ccgcggccgc cctcgggtgt
     3661 cctcgcgccc gagatgcgga ggaactgcga ggagcggggc tctgggcggt tccagaacag
     3721 ctgctaccct tggtggggtg gctccggggg aggtatcgca gcggggtctc tggcgcagtt
     3781 gcatctccgt attgagtgcg aagggaggtg cccctattat tatttgacac cccccttgta
     3841 tttatggagg ggtgttaaag cccgcggctg agctcgccac tccagccggc gagagaaaga
     3901 agaaaagctg gcaaaaggag tgttggacgg gggcggtact gggggtgggg acgggggcgg
     3961 tggagaggga aggttgggag gggctgcggt gccggcgggg gtaggagagc ggctagggcg
     4021 cgagtgggaa cagccgcagc ggaggggccc cggcgcggag cggggttcac gcagccgcta
     4081 gcgcccaggc gcctctcgcc ttctccttca ggtggcgcaa aactttgtgc cttggatttt
     4141 ggcaaattgt tttcctcacc gccacctccc gcggcttctt aagggcgcca gggccgattt
     4201 cgattcctct gccgctgcgg ggccgactcc cgggctttgc gctccgggct cccgggggag
     4261 cgggggctcg gcgggcacca agccgctggt tcactaagtg cgtctccgag atagcagggg
     4321 actgtccaaa gggggtgaaa gggtgctccc tttattcccc caccaagacc acccagccgc
     4381 tttaggggat agctctgcaa ggggagaggt tcgggactgt ggcgcgcact gcgcgctgcg
     4441 ccaggtttcc gcaccaagac ccctttaact caagactgcc tcccgctttg tgtgccccgc
     4501 tccagcagcc tcccgcgacg atgcccctca acgttagctt caccaacagg aactatgacc
     4561 tcgactacga ctcggtgcag ccgtatttct actgcgacga ggaggagaac ttctaccagc
     4621 agcagcagca gagcgagctg cagcccccgg cgcccagcga ggatatctgg aagaaattcg
     4681 agctgctgcc caccccgccc ctgtccccta gccgccgctc cgggctctgc tcgccctcct
     4741 acgttgcggt cacacccttc tcccttcggg gagacaacga cggcggtggc gggagcttct
     4801 ccacggccga ccagctggag atggtgaccg agctgctggg aggagacatg gtgaaccaga
     4861 gtttcatctg cgacccggac gacgagacct tcatcaaaaa catcatcatc caggactgta
     4921 tgtggagcgg cttctcggcc gccgccaagc tcgtctcaga gaagctggcc tcctaccagg
     4981 ctgcgcgcaa agacagcggc agcccgaacc ccgcccgcgg ccacagcgtc tgctccacct
     5041 ccagcttgta cctgcaggat ctgagcgccg ccgcctcaga gtgcatcgac ccctcggtgg
     5101 tcttccccta ccctctcaac gacagcagct cgcccaagtc ctgcgcctcg caagactcca
     5161 gcgccttctc tccgtcctcg gattctctgc tctcctcgac ggagtcctcc ccgcagggca
     5221 gccccgagcc cctggtgctc catgaggaga caccgcccac caccagcagc gactctggta
     5281 agcgaagccc gcccaggcct gtcaaaagtg ggcggctgga tacctttccc attttcattg
     5341 gcagcttatt taacgggcca ctcttattag gaaggagaga tagcagatct ggagagattt
     5401 gggagctcat cacctctgaa accttgggct ttagcgtttc ctcccatccc ttccccttag
     5461 actgcccatg tttgcagccc ccctccccgt ttgtctccca cccctcagga atttcattta
     5521 ggtttttaaa ccttctggct tatcttacaa ctcaatccac ttcttcttac ctcccgttaa
     5581 cattttaatt gccctggggc ggggtggcag ggagtgtatg aatgaggata agagaggatt
     5641 gatctctgag agtgaatgaa ttgcttccct cttaacttcc gagaagtggt gggatttaat
     5701 gaactatcta caaaaatgag gggctgtgtt tagaggctag gcagggcctg cctgagtgcg
     5761 ggagccagtg aactgcctca agagtgggtg ggctgaggag ctgggatctt ctcagcctat
     5821 tttgaacact gaaaagcaaa tccttgccaa agttggactt ttttttttct tttattcctt
     5881 cccccgccct cttggacttt tggcaaaact gcaatttttt tttttttatt tttcatttcc
     5941 agtaaaatag ggagttgcta aagtcatacc aagcaatttg cagctatcat ttgcaacacc
     6001 tgaagtgttc ttggtaaagt ccctcaaaaa taggaggtgc ttgggaatgt gctttgcttt
     6061 gggtgtgtcc aaagcctcat taagtcttag gtaagaattg gcatcaatgt cctatcctgg
     6121 gaagttgcac ttttcttgtc catgccataa cccagctgtc tttcccttta tgagactctt
     6181 accttcatgg tgagaggagt aagggtggct ggctagattg gttctttttt tttttttttc
     6241 cttttttaag acggagtctc actctgtcac taggctggag tgcagtggcg caatcaacct
     6301 ccaaccccct ggttcaagag attctcctgc ctcagcctcc caagtagctg ggactacagg
     6361 tgcacaccac catgccaggc taatttttgt aattttagta gagatggggt ttcatcgtgt
     6421 tggccaggat ggtctctcct gacctcacga tccgcccacc tcggcctccc aaagtgctgg
     6481 gattacaggt gtgagccagg gcaccaggct tagatgtggc tctttgggga gataattttg
     6541 tccagagacc tttctaacgt attcatgcct tgtatttgta cagcattaat ctggtaattg
     6601 attattttaa tgtaaccttg ctaaaggagt gatttctatt tcctttctta aagaggagga
     6661 acaagaagat gaggaagaaa tcgatgttgt ttctgtggaa aagaggcagg ctcctggcaa
     6721 aaggtcagag tctggatcac cttctgctgg aggccacagc aaacctcctc acagcccact
     6781 ggtcctcaag aggtgccacg tctccacaca tcagcacaac tacgcagcgc ctccctccac
     6841 tcggaaggac tatcctgctg ccaagagggt caagttggac agtgtcagag tcctgagaca
     6901 gatcagcaac aaccgaaaat gcaccagccc caggtcctcg gacaccgagg agaatgtcaa
     6961 gaggcgaaca cacaacgtct tggagcgcca gaggaggaac gagctaaaac ggagcttttt
     7021 tgccctgcgt gaccagatcc cggagttgga aaacaatgaa aaggccccca aggtagttat
     7081 ccttaaaaaa gccacagcat acatcctgtc cgtccaagca gaggagcaaa agctcatttc
     7141 tgaagaggac ttgttgcgga aacgacgaga acagttgaaa cacaaacttg aacagctacg
     7201 gaactcttgt gcgtaaggaa aagtaaggaa aacgattcct tctaacagaa atgtcctgag
     7261 caatcaccta tgaacttgtt tcaaatgcat gatcaaatgc aacctcacaa ccttggctga
     7321 gtcttgagac tgaaagattt agccataatg taaactgcct caaattggac tttgggcata
     7381 aaagaacttt tttatgctta ccatcttttt tttttcttta acagatttgt atttaagaat
     7441 tgtttttaaa aaattttaag atttacacaa tgtttctctg taaatattgc cattaaatgt
     7501 aaataacttt aataaaacgt ttatagcagt tacacagaat ttcaatccta gtatatagta
     7561 cctagtatta taggtactat aaaccctaat tttttttatt taagtacatt ttgcttttta
     7621 aagttgattt ttttctattg tttttagaaa aaataaaata actggcaaat atatcattga
     7681 gccaaatctt aagttgtgaa tgttttgttt cgtttcttcc ccctcccaac caccaccatc
     7741 cctgtttgtt ttcatcaatt gccccttcag agggcggtct taagaaaggc aagagttttc
     7801 ctctgttgaa atgggtctgg gggccttaag gtctttaagt tcttggaggt tctaagatgc
     7861 ttcctggaga ctatgataac agccagagtt gacagttaga aggaatggca gaaggcaggt
     7921 gagaaggtga gaggtaggca aaggagatac aagaggtcaa aggtagcagt taagtacaca
     7981 aagaggcata aggactgggg agttgggagg aaggtgagga agaaactcct gttactttag
     8041 ttaaccagtg ccagtcccct gctcactcca aacccaggaa ttctgcccag ttgatgggga
     8101 cacggtggga accagcttct gctgccttca caaccaggcg ccagtcctgt ccatgggtta
     8161 tctcgcaaac cccagaggat ctctgggagg aatgctacta ttaaccctat ttcacaaaca
     8221 aggaaataga agagctcaaa gaggttatgt aacttatctg tagccacgca gataatacaa
     8281 agcagcaatc tggacccatt ctgttcaaaa cacttaaccc ttcgctatca tgccttggtt
     8341 catctgggtc taatgtgctg agatcaagaa ggtttaggac ctaatggaca gactcaagtc
     8401 ataacaatgc taagctctat ttgtgtccca agcactccta agcattttat ccctaactct
     8461 acatcaaccc catgaaggag atactgttga tttccccata ttagaagtag agagggaagc
     8521 tgaggcacac aaagactcat ccacatgccc aagattcact gatagggaaa agtggaagcg
     8581 agatttgaac ccaggctgtt tactcctaac ctgtccaagc cacctctcag acgacggtag
     8641 gaatcagctg gctgcttgtg agtacaggag ttacagtcca gtgggttatg ttttttaagt
     8701 ctcaacatct aagcctggtc aggcatcagt tccccttttt ttgtgattta ttttgttttt
     8761 attttgttgt tcattgttta atttttcctt ttacaatgag aaggtcacca tcttgactcc
     8821 taccttagcc atttgttgaa tcagactcat gacggctcct gggaagaagc cagttcagat
     8881 cataaaataa aacatattta ttctttgtca tgggagtcat tattttagaa actacaaact
     8941 ctccttgctt ccatcctttt ttacatactc atgacacatg ctcatcctga gtccttgaaa
     9001 aggtattttt gaacatgtgt attaattata agcctctgaa aacctatggc ccaaaccaga
     9061 aatgatgttg attatatagg taaatgaagg atgctattgc tgttctaatt acctcattgt
     9121 ctcagtctca aagtaggtct tcagctccct gtactttggg attttaatct accaccaccc
     9181 ataaatcaat aaataattac tttctttgac tctgactcct agaataatct attcaaaacc
     9241 ttaatgtctt tttcttgatc cttcttttga gtcctaagta ccgccattac agcttcaaat
     9301 tggcacgtca tataggcgaa tttcaaaggg agatgcaatc cacagaagta tagtagttca
     9361 aagggttaca aaagcaaggc gctcttaaac agctcagtct ttgccccttt gtggcctagg
     9421 gctggagtgc agctctgggg tgactcactt gggaatcggg aaggtgttag tctgaatcac
     9481 taagtccagg caagccctca gaataggaga gagtgttcct agcaaggaaa acaactctcc
     9541 attccaaata atcaggaaag aactttaggg atgtggagct tggctatggg aatagaaagg
     9601 aaccattcca agtgcctatt aggccgctct tacctttact gagccagaga atggctctga
     9661 aaacaggaca gatgccaact tccttcccga aagtcaggct gatcttgacc acaatacaaa
     9721 ttggccctta gagcctatac agggagatcc caggggtctc tgccattgtg caacctattt
     9781 tgtagataat aatcaagaat cggacgtgaa ggggaggagt ttgcaacttg gtcaggaatg
     9841 tataagaagg aataagctaa ttctgactat gccctttatc catgacacta tccaggaatt
     9901 aatgactctc ccagaggatt cctggaatga ttttgttgag ggatggaatg tataaagagg
     9961 aaggaagtgt tattttatgc tgccatttgg aagcaacaaa ggagatcaac agtatgaaaa
    10021 caatcaatca aatttgaaaa tgaacaaagt tttcacaatc ccagcctaat acttagagag
    10081 ctcacagctt ggatgcataa gtaaagagtt ctctgctggt ctttaagaca aactctcaca
    10141 caaaacttgg gaaaaaggac aaaaatgttg cattaggggg ttttctgtgg tttgtttgca
    10201 ataactataa ttggctcaat caataattat tttttagtat acacactaag ggcccctgta
    10261 gcattttttc ccatcgataa ataatcctta gtctagaaaa tgccgaggga tgttctccac
    10321 ccttgtctat aaatgcactt ctagatgact ttataaaagg ctcctccttc aagtttatag
    10381 aatattataa gactacatta aaggagaaga gaggccggtc gaggtagctc acacctgtaa
    10441 tcccagcact ttgggaggcc gaagtgggcg gatcatgagg tcaggagatg gagaccatcc
    10501 tggctaaaac agtgaaaccc cgtctctact aaaaatacaa aaaattagcc gggcgtggtg
    10561 gcacagcctg cagtcccagc tactcaggag gctgaggcag gagaatcgct tgaacctggg
    10621 aggcagaggt tacagtgagc tgagattgtg ccactgcatt ccagcctgga tgacacagcg
    10681 agactccgtc tcaaaaataa ataaataata aataaataaa taaataaagg agaaaaagta
    10741 aaaacaaagc cagtaggatg ggagcaagga cttattttta aaaataaaac taaaaagact
    10801 ctgctaccta cctccaaagc cttagcaaaa agtctttttt ctagctcctt caggagagaa
    10861 cttacaccaa ctctccattt agaggaaaac acccagaaat gctggctttg ccaaactggt
    10921 tggagacgac tgtaaatgac tgtaagttga tttcattttt aattttattt tattcactat
    10981 tagcttatac taagct
//



ID   HSMYCBL3   standard; DNA; HUM; 1037 BP.
XX
AC   K00534;
XX
SV   K00534.1
XX
DT   13-JUN-1985 (Rel. 06, Created)
DT   02-JUL-1999 (Rel. 60, Last updated, Version 9)
XX
DE   Human translocated t(8;14) c-myc (MYC) oncogene, exon 2.
XX
KW   c-myc proto-oncogene; chromosomal translocation;
KW   heavy chain mu switch region; myc oncogene; transformed cell line;
KW   transforming gene; translocation; viral homology.
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Primates; Catarrhini; Hominidae; Homo.
XX
RN   [1]
RP   1-1037
RX   MEDLINE; 84026482.
RA   Battey J., Moulding C., Taub R., Murphy W., Stewart T., Potter H.,
RA   Lenoir G., Leder P.;
RT   "The human c-myc oncogene: structural consequences of translocation into
RT   the IgH locus in Burkitt lymphoma";
RL   Cell 34(3):779-787(1983).
XX
DR   SWISS-PROT; P01106; MYC_HUMAN.
XX
CC   See comments in other segments of this entry.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1037
FT                   /db_xref="taxon:9606"
FT                   /sex="female"
FT                   /organism="Homo sapiens"
FT                   /cell_line="IARC-BL22 (Congolese)"
FT                   /cell_type="Burkitt's lymphoma"
FT                   /tissue_lib="lambda Charon 4a 9 kb EcoRI fragment library
FT                   of BL22 genome"
FT                   /map="8q24"
FT   prim_transcript 1
FT   intron          order(K01708.1:797..>910,<1..137)
FT                   /note="~ 1386 bp gap; G00-120-208"
FT                   /gene="MYC"
FT   exon            138..906
FT                   /note="G00-120-208"
FT                   /number=2
FT                   /gene="MYC"
XX
SQ   Sequence 1037 BP; 199 A; 367 C; 282 G; 189 T; 0 other;
     cccagccgct ttaggggata gctctgcaag gggagaggtt cgggactgtg gcgcgcactg        60
     cgcgctgcgc caggtttccg caccaagacc cctttaactc aagactgcct cccgctttgt       120
     gtgccccgct ccagcagcct cccgcgacga tgcccctcaa cgttagcttc accaacagga       180
     actatgacct cgactacgac tcggtgcagc cgtatttcta ctgcgacgag gaggagaact       240
     tctaccagca gcagcagcag agcgagctgc agcccccggc gcccagcgag gatatctgga       300
     agaaattcga gctgctgccc accccgcccc tgtcccctag ccgccgctcc gggctctgct       360
     cgccctccta cgttgcggtc acacccttct cccttcgggg agacaacgac ggcggtggcg       420
     ggagcttctc cacggccgac cagctggaga tggtgaccga gctgctggga ggagacatgg       480
     tgaaccagag tttcatctgc gacccggacg acgagacctt catcaaaaac atcatcatcc       540
     aggactgtat gtggagcggc ttctcggccg ccgccaagct cgtctcagag aagctggcct       600
     cctaccaggc tgcgcgcaaa gacagcggca gcccgaaccc cgcccgcggc cacagcgtct       660
     gctccacctc cagcttgtac ctgcaggatc tgagcgccgc cgcctcagag tgcatcgacc       720
     cctcggtggt cttcccctac cctctcaacg acagcagctc gcccaagtcc tgcgcctcgc       780
     aagactccag cgccttctct ccgtcctcgg attctctgct ctcctcgacg gagtcctccc       840
     cgcagggcag ccccgagccc ctggtgctcc atgaggagac accgcccacc accagcagcg       900
     actctggtaa gcgaagcccg cccaggcctg tcaaaagtgg gcggctggat acctttccca       960
     ttttcattgg cagcttattt aacgggccac tcttattagg aaggagagat agcagatctg      1020
     gagagatttg ggagctc                                                     1037
//
ID   MMMYCE12   standard; DNA; ROD; 3306 BP.
XX
AC   X00195; L00038;
XX
DT   28-JAN-1986 (Rel. 08, Created)
DT   26-JUL-1991 (Rel. 28, Last updated, Version 3)
XX
DE   Mouse myc-oncogene exon 1 and exon 2
XX
KW   myc oncogene; oncogene.
XX
OS   Mus musculus (mouse)
OC   Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
OC   Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
XX
RN   [1]
RP   1-3306
RX   MEDLINE; <a href=/srs/srsc?[medline-id:84131953]>84131953</A>.
RA   Bernard O., Cory S., Gerondakis S., Webb E., Adams J.M.;
RT   "Sequence of the murine and human cellular myc oncogenes and two
RT   modes of myc transcription resulting from chromosome translocation
RT   in B lymphoid tumours";
RL   EMBO J. 2:2375-2383(1983).
XX
DR   EPD; <a href=/srs/srsc?[epd-id:14066]>14066</a>; Mm c-myc         P1.
DR   EPD; <a href=/srs/srsc?[epd-id:14067]>14067</a>; Mm c-myc         P2+.
DR   TFD; C00786; Release 7.0.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..3306
FT                   /organism="Mus musculus"
FT   promoter        79..82
FT                   /note="TATA-like sequence"
FT   promoter        200..204
FT                   /note="TATA-like sequence"
FT   promoter        397..402
FT                   /note="TATA-like sequence"
FT   mRNA            425..989
FT                   /note="exon 1"
FT   prim_transcript 1
FT                   /note=OK  promoter II
FT   intron          990..2523
FT                   /note="intron I"
FT   mRNA            2524..3295
FT                   /note="exon 2"
FT   CDS_pept        2589..3295
FT                   /note="myc-protein (aa 1-252) (3295 is 1st base in codon)"
FT                   /db_xref="PID:e7194"
FT   intron          3296..&gt;3306
FT                   /note="intron 2"
XX
SQ   Sequence 3306 BP; 692 A; 961 C; 991 G; 662 T; 0 other;
     cccgggacgt gcgtgacgcg gtccagggta catggcgtat tgtgtggagc gaggcagctg        60
     ttccacctgc ggtactgata tacgcagggc aagaacacag ttcagccgag cgctggcgcc       120
     cgaacaaccg tacagaaagg gaaaggacta gcgcgcgaga agagaaaatg gtcgggcgcg       180
     cagttaattc atgctgcgct attactgttt acaccccgga gccggagtac tgggctgcgg       240
     ggctgaggct cctcctcctc tttccccggc tccccactag ccccctcccg agttcccaaa       300
     gcagagggcg gggaaacgag aggaaggaaa aaaatagaga gaggtgggga agggagaaag       360
     agaggttctc tggctaatcc ccgcccaccc gccctttata ttccgggggt ctgcgcggcc       420
     gaggacccct ggctgcgctg ctctcagctg ccgggtccga ctcgcctcac tcagctcccc       480
     tcctgcctcc tgaagggcag cgttcgccga cgcttggcgg gaaaaagaag ggaggggagg       540
     gatcctgagt cgcagtataa aagaagcttt tcgggcgttt ttttctgact cgctgtagta       600
     attccagcga gagacagagg gagtgagcgg acggttggaa gagccgtgtg tgcagagccg       660
     cgctccgggg cgacctaaga aggcagctct ggagtgagag gggctttgcc tccgagcctg       720
     cccgcccact ctccccaacc ctgcgactga cccaacatca gcggccgcaa ccctcgccgc       780
     cgctgggaaa ctttgcccat tgcagcgggc agacacttct cactggaact tacaatctgc       840
     gagccaggac aggactcccc aggctccggg gagggaattt ttgtctattt ggggacagtg       900
     ttctctgcct ctgcccgcga tcagctctcc tgaaaagagc tcctcgagct gtttgaaggc       960
     tggatttcct ttgggcgttg gaaaccccgg taagcacaga tctggtggtc tttccctgtg      1020
     ttctttctgc gtcttgaatt gtagcggccg gttaggacag tctttcttcc attcctgtgc      1080
     ttttgacact tttctcaaga gtagttgggg taggctgggg tagatctgag tcggggtaga      1140
     gcgacttgtc aagatgacag aggaaagggg aagggaaaac cgggatgcat tttgaagcgg      1200
     ggttcccgag gttactatgg gctgacgtga cccggccggt tggacattct tgctttgcta      1260
     caggaattga tatgtgcctt tgaggggcaa accgggaggt cgcttcgtgg tggccaaaga      1320
     aagcccttgg aatcctgagg tctttggaga agggattacc ttttgcgttt gggagcgaga      1380
     aggctccgta gcttctgact taccagtctc tgagagggca tttaaatttc agcttggtgc      1440
     atttctgaca gcctgggacc gacacggagg tgcggccgcc aatccccggc ggcgatcgca      1500
     acccgtccct gagcctttaa gaagttgcta ttttggcttt aaaaatagtg atcgtagtaa      1560
     aatttagcct gacccccgcg gcacatggac ttgatgttgg ctagcgcagt gaggagaaag      1620
     caaaattggg acagggatgt gaccgattcg ttgacttggg ggaaaccaga gggaatcctc      1680
     acattcctac ttgggatccg cgggtatccc tcgcgcccct gaattgctag gaagactgcg      1740
     gtgagtcgtg atctgagcgg ttccgtaaca gctgctaccc tcggcgggga gagggaagac      1800
     gccctgcacc cagtgctgaa tcgctgcagg gtctctggtg cgagtggcgt cgcggtttag      1860
     agtgtagaag ggaggtgtct cttattattt gacaccccct ccccttttat ttcgagaggc      1920
     ttgtgatagc cggagactga gctctctcca agtcagcaat cggaaagaaa agccggcaaa      1980
     ggaaggaagg gggcgcgctg ggggtggaga aagaggaggg cggagagggg cggcggcgcg      2040
     gctgggtagg agcgcggcga cggccggaat agggactcgg acccggtcgg cggcgcagag      2100
     agccggcaca cgggaggggg ccgagcgacg cggcgcctct cgcctttctc cttcaggtgc      2160
     gcaaaacttt gcgcctcggc tcttagcaga ctgtattccc tacagtcgcc tccctcagcc      2220
     tctgaagcca aggccgatgg cgattcctgg gcgtctgcag ggctaagtcc ctgtcgaagg      2280
     aggcggggac tcggagcagc tgctagtccg acgagcgtca ctgatagtag ggagtaaaag      2340
     agtgcatgcc tcccccccaa ccacacacac acacacacac acacacacac acacacacac      2400
     acttggaagt acagcacgct gaaaggggag tggttcagga ttggggtacg ccgtgcgcca      2460
     ggtttccgca ccaaccagag ctggataact ctagacttgc ttcccttgct gtgccccctc      2520
     cagcagacag ccacgacgat gcccctcaac gtgaacttca ccaacaggaa ctatgacctc      2580
     gactacgact ccgtacagcc ctatttcatc tgcgacgagg aagagaattt ctatcaccag      2640
     caacagcaga gcgagctgca gccgcccgcg cccagtgagg atatctggaa gaaattcgag      2700
     ctgcttccca ccccgcccct gtccccgagc cgccgctccg ggctctgctc tccatcctat      2760
     gttgcggtcg ctacgtcctt ctccccaagg gaagacgatg acggcggcgg tggcaacttc      2820
     tccaccgccg atcagctgga gatgatgacc gagttacttg gaggagacat ggtgaaccag      2880
     agcttcatct gcgatcctga cgacgagacc ttcatcaaga acatcatcat ccaggactgt      2940
     atgtggagcg gtttctcagc cgctgccaag ctggtctcgg agaagctggc ctcctaccag      3000
     gctgcgcgca aagacagcac cagcctgagc cccgcccgcg ggcacagcgt ctgctccacc      3060
     tccagcctgt acctgcagga cctcaccgcc gccgcgtccg agtgcattga cccctcagtg      3120
     gtcttcccct acccgctcaa cgacagcagc tcgcccaaat cctgtacctc gtccgattcc      3180
     acggccttct ctccttcctc ggactcgctg ctgtcctccg agtcctcccc acgggccagc      3240
     cctgagcccc tagtgctgca tgaggagaca ccgcccacca ccagcagcga ctctggtaag      3300
     ctaccc                                                                 3306
//


ID   RNCMYC     standard;  DNA; ROD; 7225 BP.
XX
AC   Y00396;
XX
XX
DT   29-NOV-1987  (Rel. 14, Created)
DT   08-MAY-1993  (Rel. 35, Last updated, Version 3)
XX
DE   Rat c-myc oncogene and flanking regions
XX
KW   myc cellular oncogene; oncogene.
XX
OS   Rattus norvegicus (Norway rat)
OC   Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Rodentia;
OC   Sciurognathi; Muridae; Murinae; Rattus.
XX
RN   [1]
RA   1-7225
RA   Hayashi K.;
RT   ;
RL   Submitted (11-AUG-1987) to the EMBL/GenBank/DDBJ databases.
RL   Dr. Kenshi Hayashi, Biochemistry Division, National Cancer Center Res.
RL   Inst., 1-1, Tsukiji 5-chome, Chuo-ku, Tokyo 104, Japan.
XX
RN   [2]
RA   1-7225
RA   Hayashi K., Makino R., Kawamura H., Arisawa A., Yoneda K.;
RT   "Characterization of rat c-myc and adjacent region";
RL   Nucleic Acids Res. 15:6419-6436(1987).
XX
DR   EPD; 16061; Rn c-myc         P1.
DR   EPD; 16062; Rn c-myc         P2+.
DR   SWISS-PROT; P09416; MYC_RAT.
DR   TFD; C00689; Release 7.0.
DR   TRANSFAC; R04631; RAT$CMYC_01.
DR   TRANSFAC; T00142; T00142.
XX
CC   Data kindly reviewed (27-OCT-1987) by Hayashi K.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..7225
FT                   /organism="Rattus norvegicus"
FT                   /strain="Buffalo"
FT                   /tissue_type="liver and hepatoma"
FT   mRNA            join(2169..2569,4151..4919,5919..6916)
FT   CDS             join(4163..4919,5919..6483)
FT                   /db_xref="PID:e75129"
FT                   /db_xref="SWISS-PROT:P09416"
FT                   /product="c-myc protein"
FT   misc_feature    1225..1248
FT                   /note="pot. nuclear factor 1 binding site"
FT   promoter        1976..1981
FT                   /note="first TATA - box"
FT   misc_feature    2004..2004
FT                   /note="minor transcription initiation site"
FT   promoter        2136..2141
FT                   /note="second TATA - box"
FT   prim_transcript 1 
FT                   /note=OK exact coincedence with the aligment
FT   exon            2169..2569
FT                   /number=1
FT   intron          2570..4150
FT                   /number=1
FT   exon            4151..4919
FT                   /number=2
FT   intron          4920..5918
FT                   /number=2
FT   exon            5919..6916
FT                   /number=3
FT   misc_feature    6702..6706
FT                   /note="ATTTA destabilizing sequence"
FT   polyA_signal    6766..6776
FT                   /note="pot. polyA signal"
FT   misc_feature    6830..6834
FT                   /note="ATTTA destabilizing sequence"
FT   polyA_signal    6884..6894
FT                   /note="pot. polyA signal"
FT   polyA_site      6916
FT                   /note="polyA site"
XX
SQ   Sequence 7225 BP; 1754 A; 1906 C; 1883 G; 1682 T; 0 other;
     aagcttcttc ccagaacctg gaagcccagc aagcaaatgc cctgccccca cccgacctcc
     gccctcgttg gcttcgcaaa gctgtgatct gtggccagta gagggcacac tttactttcg
     caaatctgag agccacaacc cgggggaggg ggcggggaaa gagtctctgc agcaaaatgc
     agcctaggga ttggtggctc ttggcgtttg aggcaaaatc ctagaggctg tagtcatttt
     gcaatcctta aagctgaatt gtgcaatgag ctcgatgaag gaagatacta tcatccaaca
     gctgaatcct aaattgcaaa ctcaatggct aatgactact ttgaacaatg cgcaccttac
     acacgctaca cgctactgta gtctcttctt tttttagggg gtagcagtga gaggtttctt
     aaaatgcctt ggggcgagga gtcctgaatg aggagactgc tttgggtttt gatgcgtagg
     ataagcaaat cccgaggaaa tatgcactat ataataaatc tagaaccaaa acacagagca
     aaagattcat gtttcacgtt ggttaataaa ctaggttatc gtgtatatat taagtgtgta 600
     tacctttggg gactctacaa aatgcacggc atggtattga ggaaaaagta aattgggaaa
     ttagtgtaaa aattagagtc ggcttttaat tagtttaaca cacacatacg aaggcaaaga
     cacaacgtta ctttgatctg accggggccg accttttttt aagtgcataa ttacgattcc
     agtaataaaa ggggaaagtt tggggtttgt cctgagagga aggggttaac ggtttccttt
     attctagggt ctccgcaggc tccccagatc tgggttggca attctactcc tccccctttc
     tgggaagtcc gggtttcccc caacccccaa tccatggcat attctcgcgt ctagcgcctt
     gattcccgcc cccccacacc cccaacctct aagccggagt ctggtgcaaa ctggctccac
     aggggcaaag aggatttgcc tttagtggaa actggctgtg gaactggaac tctgagtgga
     ggtgcatggg gtgtagactg gcagagactc gaccgggagg atccgggtag agcgcgccca
     ccgccgcagt cctactctac tccagctctg gaacgcgcag aaagacctac ggggcaagga 1200
     gccgcctcca ccccaccccg cctggtggaa ggtccgaacg ggaggtgttg gagtggaggg
     cctttctggc agcaaattgg gggattcatt ctgtaaagaa tgtgcccagt caacatagct
     gtacgcccaa acgcaaaata cacactgccc tccccgagag atgcagtggc tgtttattcc
     taagtggctc tccaagtata cgtggcattg agttgctgag caattttaat gattccaggc
     atcgtttttc tgctcagacc tcatctgtcg taggtcttca actatcactc cacactgagc
     aagggctcct acataactct tttttttttt cgtccttccc tttttaaatt ctgtttcccc
     gaccttagag agacgactgg ccgcccgaga cgtgcgtgac gcggctcagg gtacacggcg
     tattgtgtgg agcgaggcag ctgttccacc tgcggtgact aatacacgca ggacaagaac
     acagttcagc cgagcgctgc gcccgaacaa ctgtacagaa agggaaagga ccgacgcgcg
     agcaggagaa aatggtcggg cgcgcagtta attcatgctg cgctattact gtttacaccc 1800
     cgagtcggag tactgggctg cgggactgag gctcctcctc tttccccggc tccccactag
     tgcccctccc gagttcccaa agcagagggc gggggagcga gaggaggaaa aaaatagagg
     tcgggagggg agggagaaag agattctctg gcctaatccc cgcccacccg ccctttataa
     tccgggggtc tgcgcggcta aggacccccg ggctgcgctg ctctccgctg ccgcctccgc 2040
     cgcgcccact ccgctcgcct cctgcctcca aaagggcagg cgttcgccga ggcttggcgg 2100
     gaaaaagaag cgaggggagg gatccggagt cgcagtataa aagaagcttt tcgggcgttt
     tttttctgac tcgctgtagt aattccagcg agagacagag ggagtgagcg ggcgggttgg
     aagagcccag tgtgcagagc cccactccgg gcttcctagg aaggcagctc tggagtgaga
     agggctttgc ctccaggctt gctgcctcct cgacccaatc ctcccgctga cccaacatca 2340
     gcggtcgcaa ccctcgccgc ctctgggaaa ctttgcccat tgcaacgggc agacacttct
     cactggaact tacaatctgc gagccaggac aggactcccc aggcgcaggg gagggaattt
     ttgtctattt ggggacagtg ttctctgcct ctgcccgcga tcggctcccc tgaaaagagc
     tcctcgcgtt atttgaagcc tgaatttcct ttgggaggtg gaaaacccgg taagcacaga
     tctgttggtc ttctactgtt ttctctacgt cctgagtgta gcgaccggtt agaacagtct
     ttattcaatt tctgtgcttt tgacacttta ctcagagtag ttggggtagg ccggggcgga
     gttggggtgg atctgagtcg gggtagaacg acttgtcaag atgacaggaa aggggaagga
     aaaaaccggg gtgcattttg aaactgtctt ccagaggtta ccgtgggctg acgctgaccc
     gggccggttg gacattcttg ctgtgctaca ttaattgata tttatgtcct ttgggggggg
     ggtgtcaaag ccggaggtct cttcgcggtg gccaaaggaa gcccttcgta tcctgaggtc
     tttgggaaag ggattacctt ttgcgtgttc tccgcaaaaa gcgagaaggc tccgtagcct
     ctgacttccc agtctttggg agggcattta aatttcggct tggtgcattt ctgacagcct
     gagaccaact cgggggtgcg tcccgcccgc caatccccgg cggcgattgc aaccggtccc
     tgatcctttt aagaagttgc cattgggctt taaaaatagt gatcatagta aaatttaagc
     ctaaccctcc gcggtattag gacttggtgt tggactagcg cactgaggag aggcaaaact
     ggggcaggga tgtgacagat tcgttgactt ggggaaaacc agagggaatc ctcacattcc
     tggttgggat ccgcgggtat tccccgcgcc cctgaattgc tagggagact gcggtgagtc
     ttgatctgag ctgttcggta acagctgcta ccctcggcgg ggagagggaa gacgccctgc
     accgggtgct gaatcgctgt ggggtctctg gcgcagtggc gtcgcggttt agagtgtagc
     agggaggtgt ctcttattat ttgacacccc ctcccctttg gagaggcttg ttagagcctg
     agactgagct ctcccctcca agtcagcaat aggaaagaaa agccggcaaa ggaaggaagg
     ggggcgcgct gggggtggag aaagaggagg gcggagaggg gcggcggcgc cggctgggta
     agagccgggc gacggcgcga gtagggaccc ggacccggtc ggcggcgcaa agagccggca
     ccggaggggg ccgagcaccg cggcgcctct cgcctttctc cttcaggtgg cgcaaaactt
     tgcgcctagg cttttggcag actgtattcc ctacagtcgc ctccctcagc ctctgaagga
     ggccaaggcc gatggcgatt cctgggcgtc tgcagtgcta agtccctgct ctaaggaggc
     ggggactccg agcagctgct agtccgacca gcgtcactga tagtagggag taaaagagtg
     cattcccccc aaccacacac acacacacac acacacacac acacacacac acacacacac
     acacacttgg aagtacagca ggctgaaagg ggagtggttc aggattgggg tacgcgctgc
     gccaggtttc cgcatcaacc agagctgggt aactctagac ttgcttccct tgctgtgccc
     cctccaacag acagtcacga cgatgcccct caacgtgagc ttcgctaaca ggaactatga
     cctcgactac gactcggtgc agccctattt catctgcgac gaggaagaga atttctatca
     ccagcaacag cagagcgagc tgcagccgcc cgcacccagt gaggatatct ggaagaaatt
     cgagctgctg cccaccccgc ccctgtcccc cagccgccgc tccgggctct gctctccgtc
     ctatgtcgcg gtcgctacgt ccttctcccc aagggaggac gatgacggtg gcggtggcaa
     cttctccacc gccgatcagc tggagatgat gaccgagcta cttggaggag acatggtgaa
     tcagagcttc atctgcgatc ctgacgatga gaccttcatc aagaacatca tcatccagga
     ctgtatgtgg agcggcttct cggccgctgc caaactggtc tccgagaagc tggcctctta
     ccaggctgcg cgcaaagaca gcaccagcct gagccccgcc cgcgggcaca gcgtctgctc
     cacctccagc ctgtacctgc aggacctcac cgccgcagcg tccgagtgca tcgacccctc
     agtggtcttc ccctacccgc tcaacgacag cagctcgccc aaatcctgta cctcgtccga
     ttccacggcc ttctcttctt cctcggactc gctgctgtcc tccgagtcct ccccacgggc
     cacccctgag cccctagtgc tgcatgaaga gacaccgccc accaccagca gcgactctgg
     taagccgccc caaccccagc agggtaggaa gccagaggtt ggatggacct ccttctcatt
     ggcattaatt caattggccc ccgggctcac cctttctttc ccttcggtct aagctcttca
     tccctggact cctgtgcttc agatatccct ccccttcccc cagaccgccc tggttgtcag
     ccccaccccc acccttccca cccctcagga atttcatttg ggtttttaaa tcttctggct
     tatctttcaa ctcaatccac tccctttacc cctcctaggc attttaatta cccagagaag
     ggtgtgaagg aggataggga actgatcctg agaagagtga atgaattacc tgcttttctt
     tgacttcaga agaatatttg aatttaatgt ctacaagacc caagagaagc aatgacagaa
     gcaggacagc ctttagcctc agagccaggc actagtgaaa gatcctgaag agttgaagag
     ctgttttccc tccatcccgt tttgaacact tcaaagcaaa tcctcttcag tttggatttt
     cgtaccccct ccctccccaa atgctcgccc caccactgcc accaccagga caggacgttt
     ggcaaaacca caagacttta ctattgcact tccagtaata tagggagttg gtaaagtcat
     agcaagatat ttgcagctat cgcctacagg acctgaaggg ttcttggtga agtcccttaa
     aaatgggagg tgcttgggaa tgtgctttgc tttgggtgtg tctgaagcct cattaagtct
     taggtaagaa ttggcaacga tgccatatcc tggtacatgg taattttctc acctgtgccc
     taaccctgtt ctacctttct gggaaacggg aggatggtgt ctagatctgg ttcttacttc
     tcaatccttt ccaacttggc acttggatag catcggtcaa acccccatct gggattcagg
     aggcattgct aactaatctt ccacttcctt ccttacagaa gaagaacaag atgatgagga
     agaaattgat gtggtgtctg tggaaaagag gcaaccccct gccaagaggt ccgagtcagg
     gtcatcccca tcaagaggcc acagcaaacc tccacacagc ccactggtcc tcaagaggtg
     ccatgtctct actcaccagc acaattatgc agcacccccc tccacaagga aggactatcc
     agctgccaag agggccaagt tggacagtgg cagggtcctg aaacagatca gcaacaaccg
     caaatgctcc agccccaggt cctcagacac cgaggaaaac gacaagaggc ggacacacaa
     cgtcttggaa cgtcagagga gaaacgagct gaagcgtagc ttttttgccc tgcgcgacca
     gatccctgag ttggaaaaca acgaaaaggc ccccaaggta gttatcctca aaaaagccac
     cgcctacatc ctgtccgttc aagcagatga gcacaaactc atctcagaaa aggacttact
     gaggaaacgg cgagaacagt tgaaacacaa actcgaacag cttcgaaact ctggtgcata
     aactgaccgg aagtgaggag gagctggaat ctcgagtgta aggagaacgg ttccttctga
     cagaacttgg acttcaaaaa atgcatgctc aaagcctaac ctcacaacct tggctggggc
     tttgggactt cagccataat gttaactgcc tcaaagttaa ggcataaaag aacttttttt
     tatgcttccc atcttctttc tttttccttt aacagatttg tatttaattg ttttttttaa
     aaaaatcttc cggtgtacat agggccttta aatgtaaata actttaataa aacgtttata
     acagttatac aagattttaa gacatgtatg ataaaccata atttttttta tttaaagacc
     ttttcatttt taaagttgat ttttttctat tgtttttaga aaaaataaaa taattggaaa
     aaatataatt gagccaactc ttaaatggtg ttttcttttt tttttttcct ccaatttctc
     ttcctcaact atagatgaac agaactgacc gtcttcccag gacgggttta caagggtggg
     aaggggttat cttaaaatgg ggcgggggag gggggtgcct caagacctct aagttcccag
     tgttatgaga tcctttctgt ggatgctgat aggatgagag ttgagaaagg gcaaaaggca
     agtgaggtta gatacaagga acagggaagc aagaggttaa agatagcaga cagggaagag
     atggcagaat gaatctcctg cagtt
//


ID   PTCMYC     standard;  DNA; MAM; 6911 BP.
XX
AC   M38057;
XX
XX
DT   02-FEB-1991  (Rel. 26, Created)
DT   29-JUL-1995  (Rel. 44, Last updated, Version 4)
XX
DE   Chimpanzee c-myc proto-oncogene, complete cds.
XX
KW   c-myc proto-oncogene.
XX
OS   Pan troglodytes (chimpanzee)
OC   Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata; Vertebrata;
OC   Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Pan.
XX
RN   [1]
RA   1-6911
RA   Argaut C., Rigolet M., Eladari M.E., Galibert F.;
RT   "Cloning and nucleotide sequence of the chimpanzee c-myce gene";
RL   Gene 97:231-237(1991).
XX
DR   SWISS-PROT; P23583; MYC_PANTR.
DR   TFD; C00681; Release 7.0.
XX
CC   Draft entry and computer-readable sequence for [Gene (1990) In
CC   press] kindly submitted by F.Galibert, 29-AUG-1990. NCBI gi: 176652
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..6911
FT                   /organism="Pan troglodytes"
FT                   /sequenced_mol="DNA"
FT                   /tissue_type="blood"
FT   transl_start    560
FT                   /note=OK
FT   CDS             560..904
FT                   /codon_start=1
FT                   /db_xref="PID:g176654"
FT                   /label=ORF
FT                   /note="NCBI gi: 176654"
FT                   /translation="MRCWVILIILGIVFLLMPLSFLPIYTNIPRSERAPINTLLSSTLS
FT                   GTLDQSAALSPALARRPAAWYARGVAVGVQCVLGVEGSCSACDDLHSQDKDAVCQTVLL
FT                   RRSSRERERV"
FT   CDS             1133..1699
FT                   /codon_start=1
FT                   /db_xref="PID:g176655"
FT                   /note="NCBI gi: 176655"
FT                   /translation="MRGSGRLRTPELCCSRPPPPGPGRPWLPSCLEKGRASQRLGGKKN
FT                   GGRDRAEYKSRFSGLYLTRCSNSSERQRERAGGRLGWKSRASRAALRASWEGRSGANRG
FT                   LRLWPSPPADPPASGPQPLPHPRNFAHSSGRALCTGTYNTRARTRLSRRGEAILPIWGH
FT                   FPAAARTRFSERLSLQLLRRWIFFG"
FT   prim_transcript 1319 according to the alignment
FT                   /note=OK
FT   CDS             join(3354..4110,5482..6044)
FT                   /codon_start=1
FT                   /db_xref="PID:g176653"
FT                   /db_xref="SWISS-PROT:P23583"
FT                   /note="NCBI gi: 176653"
FT                   /translation="MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAP
FT                   SEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTE
FT                   LLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPN
FT                   PARGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCPSQDSSAFSPSSDS
FT                   LLSSTESSPQGSPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGS
FT                   PSAGGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNR
FT                   KCTSPRSSDTEENDKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKA
FT                   TAYILSVQAEEQKLISEEDLLRKRREQLKHKLEQLRNSCA"
FT   start_transl    3354
FT                   /note=OK
FT   exon            <3354..4110
FT   intron          4111..5481
FT   exon            5482..>6044
XX
SQ   Sequence 6911 BP; 1542 A; 1853 C; 1869 G; 1647 T; 0 other;
     aacggttttt ttcacaaggg tctctgctga ctcccccggc tcggtccaca agctctccac
     ttgccccttt taggaagtcc ggtcccgcgg ttcgggtacc ccctgcccct cccatattct
     cccgtctagc acctttgatt tctcccaaac ccggcagccc gagactgttg caaatcggcg
     ccacagggcg caaaggggat ttgtctcttc tgaaacctgg ctgagaaatt gggaactccg
     tgtgagaggc gcgggggtgg gacggtgggg tacagactgg cagagagcag gcaacctccc
     tctcgcccta gtccagctct ggaacaggca gacacatctc agggctaaac agacgcctcc
     cgcacggggc cccacggaag cctgagcagg cggggcagga ggggcggtat ctgctgcttt
     ggcagcaaat tgggggactc agtctgggtg gaaggtatcc aatccagata gctgtgcata
     cataatgcat aatacatgac tccccccaac aaatgcaatg ggagtttatt cataacgcgc
     tctccaagta tacgtggcaa tgcgttgctg ggttatttta atcattctag gcatcgtttt 600
     cctccttatg cctctatcat tcctccctat ctacactaac atcccacgct ctgaacgcgc
     gcccattaat acccttcttt cctccactct ctctgggact cttgatcaaa gcgcggccct
     ttccccagcc ttagcgaggc gccctgcagc ctggtacgcg cgtggcgtgg cggtgggcgt
     gcagtgcgtt ctcggtgtgg agggcagctg ttccgcctgc gatgatttac actcacagga
     caaggatgcg gtttgtcaaa cagtactgct acggaggagc agcagagaaa gggagagggt 900
     ttgagaggga gcaaaagaaa atggtaggcg cgcgtagtta attcatgcgg ctctcttact
     ctgtttacat cctagagcta gagtgctcgg ctgcccggct gagtctcctc cccaccttcc
     ccaccctccc caccctcccc ataagcgccc ctcccgggtt cccaaagcag agggcgtggg 1080
     ggaaaagaaa aaagatcctc tctcgctaat ctccgcccac cggcccttta taatgcgagg
     gtctgggcgg ctgaggaccc ccgagctgtg ctgctcgcgg ccgccaccgc cgggccccgg 1200
     ccgtccctgg ctcccctcct gcctcgagaa gggcagggct tctcagaggc ttggcgggaa
     aaagaacgga gggagggatc gcgctgagta taaaagccgg ttttcggggc tttatctaac
     tcgctgtagt aattccagcg agaggcagag ggagcgagcg ggcggccggc tagggtggaa
     gagccgggcg agcagagctg cgctgcgggc gtcctgggaa gggagatccg gagcgaatag
     ggggcttcgc ctctggccca gccctcccgc tgatccccca gccagcggtc cgcaaccctt
     gccgcatcca cgaaacttcg cccatagcag cgggcgggca ctttgcactg gaacttacaa
     cacccgagca aggacgcgac tctcccgacg cggggaggct attctgccca tttggggaca
     cttccccgcc gctgccagga cccgcttctc tgaaaggctc tccttgcagc tgcttagacg
     ctggattttt ttcggatagt ggaaaaccag gtaagcaccg aagtccactt gccttttaat
     ttattttttt atcactttaa tgctgagatg agtcgaatgc cgaaataggg tgtcttttct
     cccattcctg cgctattgac acttttctca gagtagttat ggtaactggg gctggggtag
     ggggtaatcc agaactggat cggggtaaag tgacttgtca agatgggaga ggagaaggca
     gagggaaaac gggaatggtt tttaagacta gactttcgag atttctgcct tatgaatata
     ttcacgctga ctcccggccg gtcggacatt cctgctttat tgtgttaatt gctgtctggg
     ttttgggggg ctgggggttg ctttgcggtg ggcagaaagc cccttgcatc ctgagctcct
     tggagtaggg accgcatatc gcctgtgtga gccagagagc tccgcagccg ctgacttgtc
     cccgtctccg ggagggcatt taaatttcgg ctcaccgcat ttctgacagc cggagacgga
     cactgcggcg cgtcccgccc gcctgtcccc gcggcgattc caacccgccc tgatcctttt
     aagaagttgg catttggctt tttaaaaagc aataatacaa tttaaaacct gggtctctag
     aggtgttagg atgcggtgtt gggtaggcgc aggcagggga aaagggaggc gaggatgtgt
     ccgattctcc tggaatcgtt gacttggaaa aaccagggcg aatctccgca cccagccctg
     actcccctgc cgcggccgcc ctcgggtgtc ctcgcgcccg agatgcggag gaactgcgag
     gagcggggct ctgggcggtt ccagaacagc tgctaccctt ggtggggtgg ctccggggga
     ggtatcgcag cggggtctct ggcgcagttg catcgccgta ttgagtgcga agggaggtgc
     ccctattatt atttgacacc ccccttgtat ttatggaggg gtgttaaagc ccgcggctga
     gctcgccact ccagccggcg agagaaagaa gaaaagccgg caaaagaagg agtgttgggc
     gggggcggta ctgggggtgg ggacgggggc ggtggagagg ggaggttggg aggggctgcc
     gtgccggcgg gggtaggaga gcggctaggg cgcgagtggg aacagccgca gcggaggggc
     cccggcgcgg gagcggggtt cacgcagccg ctagcgccca ggcgcctctc gccttctcct
     tcaggtggcg caaaactttg tgccttggat tttggcaaat tgtattcctc accgccacct
     cccgcggctt cttaagggcg ccaaggccga tttcgattcc tctgccgctg cagggccgac
     tcccgggctt tgcgctccgg gctcccgggg gagcgggggc tcggcgggca ccaagccgct
     ggttcactaa gtgcgtctcc gagatagtag gggactgtcc aaagggggtg aaagggtgct
     ccctttattc ccccaccaag accacccagc cgctttaggg gatagctctt caaggggaga
     ggttcgggac tgtggcgcgc actgcgcgct gcgccaggtt tccgcaccaa gaccccttta
     actcaagact gccttccgct ttgtgtgtcc ccctccagca gcctcccgcg acgatgcccc
     tcaacgttag cttcaccaac aggaactatg acctcgacta cgactcggtg cagccgtatt
     tctactgcga cgaggaggag aacttctacc agcagcagca gcagagcgag ctgcagcccc
     cggcgcccag cgaggatatc tggaagaaat tcgagctgct gcccaccccg cccctgtccc
     ctagccgccg ctccgggctc tgctcgccct cctacgttgc ggtcacgccc ttctcccttc
     ggggagacaa cgacggcggt ggcgggagct tctccacggc cgaccagctg gagatggtga
     ccgagctgct gggaggagac atggtgaacc agagtttcat ctgcgacccg gacgacgaga
     ccttcatcaa aaacatcatc atccaggact gtatgtggag cggcttctcg gccgccgcca
     agctcgtctc agagaagctg gcctcctacc aggctgcgcg caaagacagc ggcagcccga
     accccgcccg cggccacagc gtctgctcca cctccagctt gtacctgcag gatctgagcg
     ccgccgcctc agagtgcatc gacccctcgg tggtcttccc ctaccctctc aacgacagca
     gctcgcccaa gtcctgcccc tcgcaagact ccagcgcctt ctctccgtcc tcggattctc
     tgctctcctc gacggagtcc tccccgcagg gcagccccga gcccctggtg ctccatgagg
     agacaccgcc caccaccagc agcgactctg gtaagcgaag cccgcccagg cctgtcaaaa
     gtgggcggct ggatatcttt cccattttca ttggcagctt atttaacagg ccactcttat
     taggaaggag agatagcaga tctggagaga tttgggagct catcacctct gaaaccttgg
     gctttagcgt ttcctcccat cccttcccct tagaccgccc tcgtttgcag cccccctccc
     cgtttgtctc ccacccctca ggaatttcat ttaggttttt aaaccttctg gcttatctta
     caactcaatc cacttcttac ctcccgttaa cattttaatt gccctggggc ggggtggcag
     ggagtgtatg aatgaggata agagaggatt ggtctctgag agagtgaatg aattgcttcc
     ctcttaactt ccgagaagtg gtgggattta atgaactatc tacaaaaatg aggggctgtg
     tttagaggat aggcagggcc tgcctgagtg cgggagccag tgaactgact caagagtggg
     tgggctgagg agctgggatc ttctcagcct attttgaaca ctgaaaagca aatccttgcc
     aaagttggac tttttttttc attttttcct tcccccgccc tcttggactt ttggcaaaac
     tgcaattttt ttttcttttt catttccagt aaaataggga gttgctaaag tcataccaag
     caatttgcag ctatcatttg caacacctga agtgttcttg gtaaagtccc tcaaaaatag
     gaggtgcttg ggaatgtgct ttgctttggg tgtgtccaaa gcctcattaa gtcttaggta
     agaattggca tcaatgtcct atcctgggaa gttgcacttt tcttgtccat gccataaccc
     agctgtcctt ccctttatga gactcttacc ttcatggtga gaggagtaag ggtggctggc
     tagattggtt cttttttttt gttttttcct tttttaagac ggagtctcac tctgtcacta
     ggctggagtg cagtggcgca atcaacctcc aaccccctgg ttcaagagat tcccctgcct
     cagcctccga ggtagctggg actacaggtg cacaccacca tgccaggcta atttttgtaa
     ttttagtaga gatggggttt caccatgttg gccaggatgg tctctcctga cctcaagatc
     cgcccacctc ggcctcccaa agtgctggga ttacaggtgt gagccagggc accaggctta
     gatgtggctc tttggggagc taattttgtc cagagacctt tctaacatat taatgccttg
     tatttgtaca gcattaatct ggtaattgat tattttaatg taaccttgct aacggagtga
     tttctatttc ctttcttaaa gaggaggaac aagaagatga ggaagaaatc gatgttgttt
     ctgtggaaaa gaggcaggct cctggcaaaa ggtcagagtc tggatcacct tctgctggag
     gccacagcaa acctcctcac agcccactgg tcctcaagag gtgccacgtc tccacacatc
     agcacaacta cgcagcgcct ccctccactc ggaaggacta tcctgctgcc aagagggtca
     agttggacag tgtcagagtc ctgagacaga tcagcaacaa ccgaaaatgc accagcccca
     ggtcctcgga caccgaggag aatgacaaga ggcgaacaca caacgtcttg gagcgccaga
     ggaggaacga gctaaaacgg agcttttttg ccctgcgtga ccagatcccg gagttggaaa
     acaatgaaaa ggcccccaag gtagttatcc ttaaaaaagc cacagcatac atcctgtccg
     tccaagcaga ggagcaaaag ctcatttctg aagaggactt gttgcggaaa cgacgagaac
     agttgaaaca caaacttgaa cagctacgga actcttgtgc gtaaggaaaa gtaaggaaaa
     cgattccttc taacagaact gtcctgagca atcacctatg aacttgtttc aaatgcatga
     tcaaatgcaa cctcacaacc ttggctgagt cttgagactg aaagatttag ccataatgta
     aactgcctca aattggactt tgggcataaa agaacttttt tatgcttacc atcttttttt
     tttctttaac agatttgtat ttaagaattg tttttaaaaa attttaagat ctacacaatg
     tttctctgta aatattgcca ttaaatgtaa ataactttaa taaaacgttt atagcagtta
     cacagaattt caatcctagt atatagtacc tagtattata ggtgctataa accctaattt
     tttttattta agtacatttt gctttttaaa gttgattttt ttctattgtt tttagaaaaa
     ataaaataac tggcaaatat atcattgagc caaatcttaa gttgtgaatg ttttgtttcg
     tttcttcccc ctcccaacca ccaccatccc tgtttgtttt catcaattgc cccttcagag
     ggtggtctta agaaaggcaa gagttttcct ctgttgaaat gggtctgggg gccttaaggt
     ctttaagttc ttggaggttc taagatgctt cctggagacc atgataacag ccagagttga
     cagttagaag gaatggcaga aggccggtga gaaggtgaga ggtaggcaaa ggagatacaa
     gaggtcaaag atagcagtta agtacacaaa gaggcataag gactggggag ttgggaggaa
     ggtgaggaag aaactcctgt tactttagtt aaccagtgcc agtcccctgc tcactccaaa
     cccaggaatt c
//
